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                    Research Associate Metabolomics - Open Rank
                    Job Number: 2023-44115
                    
Category: Research
                    
Location: Worcester, MA
                    
Shift: Day
                    
Exempt/Non-Exempt: Exempt
                    
Business Unit: UMass Chan Medical School
                    
Department: School - Molecular Medicine - W400900
                    
Job Type: Full-Time
                    
Union Code: Non Union Position -W60- Non Unit Professional
                    
Num. Openings: 1
                    
Post Date: July 27, 2023
                    
                    
                    
                
 
             
            
                POSITION SUMMARY:  
We are seeking an enthusiastic and motivated individual who is interested in supporting metabolism-based research projects in the department of Molecular Medicine in a variety of experimental models using liquid-chromatography mass-spectrometry. Under the direction of the Principal Investigator (or designee) you will provide high-quality and professional operational support to our liquid-chromatography mass-spectrometry platform by performing bench level experiments. You will use discretion in prioritizing and organizing workflows. You will be expected to work independently and as part of a team to ensure high-quality data acquisition in a state-of-the-art laboratory.
This is an open-rank posting (there are four levels of Research Associate) - candidates will be hired into the level commensurate with their experience.
ESSENTIAL FUNCTIONS:
Research Associate I:
- Perform laboratory experiments and may be responsible for a single research project.
- Process and prepare samples for analysis by LCMS by following SOPs
- Perform weekly cleaning and calibration of LCMS instrumentation
- Perform data quality checks
- Utilize all software relevant to experiment and equipment used
- Interpret data, form conclusions, and decide on next steps under the direction of the PI or designee
- Maintain accurate records, may modify protocols with the approval of the PI or designee
- Review literature, publications and grants relevant to assigned projects
- Record results according to established lab, sponsor & university protocol
- Assist with performing data analysis and/or mathematical computations
- Maintain a detailed lab notebook according to lab practice
- Present findings at lab/group meetings
- Monitor laboratory supply levels and order as needed.
- Prepare and label buffers, media, solutions, etc and clean laboratory glassware
- Assist with and comply with all safety regulations and infection control standards.
- Train on IACUC, IRB, EHS, Radiation safety protocols
- Comply with all applicable state, federal university, and sponsor policies and agreements
- Provide support with identifying problems and challenges, propose resolutions, implement appropriate solutions
- Provide support with drafting standard operation procedures in compliance to EHS regulation specific for the lab
- Perform other duties as required
Research Associate II:
Essential functions noted above plus:
- May assist with the training of new lab personnel
- Provide support with drafting standard operation procedures in compliance to EHS regulation specific for the lab
- May assist with drafting manuscripts
- Process and prepare samples for analysis by LCMS by following SOPs
- Perform weekly cleaning and calibration of LCMS instrumentation
- Perform data quality checks
- Attend team meetings. May participate in scientific conferences and contribute to scientific journals
- Consult with literature and scientific colleagues to maintain professional expertise
Research Associate III:
Essential functions noted above plus:
- Perform complex laboratory experiments and may be responsible for one or more independent research projects
- Perform in-depth data analysis and/or mathematical computations
- Compile and analyze data and present it in a format suitable for publication according to PI specifications
- May oversee laboratory supply levels and order as needed; negotiate with suppliers to optimize available resources
- Monitor laboratory equipment service contracts and monitor maintenance on laboratory equipment
- May manage general operations of the laboratory, including lab personnel, procedures, and projects
- May create new protocols and/or modify defined protocols, as necessary, and with the approval of the PI
- Prioritize and perform several tasks or procedures simultaneously with diligence
- Perform duties and experiments with independence
- Provide training of new lab personnel
- May monitor laboratory spending in accordance with budget guidelines provided by PI or designee
- May assist with budget and/or operational aspects of grant and contract funding.
- May assist with the training of new lab personnel
- Provide support with drafting standard operation procedures in compliance to EHS regulation specific for the lab
- May assist with drafting manuscripts
- Process and prepare samples for analysis by LCMS by following SOPs
- Organize laboratory supplies and orders as necessary to maintain laboratory stocks
- Perform weekly cleaning and calibration of LCMS instrumentation.
- Perform data quality checks
- Attend team meetings. May participate in scientific conferences and contribute to scientific journals
Research Associate IV:
Essential functions noted above plus:
- This position will contribute significantly to the management of the research program and will be involved in multiple aspects of the research projects and lab maintenance activities
- Independently design and perform multiple complex laboratory experiments.
- Interpret data, form conclusions, and decide on next steps with a high degree of independence
- Maintain laboratory supply levels and order as needed
- Manage laboratory equipment service contracts and coordinate maintenance on laboratory equipment
- Monitor and enforce all safety regulations and infection control standards
- Identify and write standard operation procedures in compliance to EHS regulation specific for the lab
- Train on IACUC, EHS, Radiation safety protocols
- Manage daily operations of the laboratory, including lab personnel, procedures, and projects
- Identify problems and challenges, propose resolutions, implement appropriate solutions
- Develop and implement new protocols and/or modify defined protocols, as necessary, and with the approval of the PI
- Mentor and train lab personnel on proper lab conduct and techniques
- Manage laboratory spending in accordance with budget guidelines provided by PI or designee
- Assist with budget and/or operational aspects of grant and contract proposals
- Negotiate with vendors to optimize available resources
- Contribute independently to writing sections for manuscripts and grants
- Direct the activities of research support staff
- Perform weekly cleaning and calibration of LCMS instrumentation
- Perform data quality checks
- Attend team meetings. May participate in scientific conferences and contribute to scientific journals
REQUIRED QUALIFICATIONS:
Research Associate I
- Bachelors degree in biological science/biochemistry/(analytical) chemistry, or a field directly related to the work
- Basic understanding of lab safety and protocols
- Proficient in basic molecular biology and biochemical techniques, including working with micropipettes and buffer making
- Knowledge of Microsoft Office products
- Experience with electronic laboratory notebooks
- Ability to analyze data in a quantitative and objective manner.
- Ability to work in a team environment.
Research Associate II
Requirements noted for RA I plus:
- 18 months of relevant research experience with a bachelors degree in biological science/biochemistry/(analytical) chemistry or 0 years with a related masters degree.
Research Associate III
Requirements noted for RA I plus:
- 3+ years of relevant research experience with a bachelors degree in biological science/biochemistry/(analytical) chemistry or 1-year relevant research experience with a related masters degree
- Experience with chromatography and/ or mass spectrometry
Research Associate IV
Requirements noted for RA I plus:
- 5+ years of relevant research experience with a bachelors degree in biological science/biochemistry/(analytical) chemistry or 3+ years relevant research experience with a related Masters degree or Ph.D.
- Experience analyzing small molecules using chromatography and/or mass spectrometry
PREFERRED QUALIFICATIONS (ALL LEVELS):
- Interest in advanced data processing and analysis (use of Matlab, R, Python etc).
- Familiarity with statistical models used to analyze large datasets
                Posting Disclaimer:
                This job posting outlines the primary responsibilities and qualifications for the role but is not intended to be an exhaustive list. 
                Duties and expectations may evolve in response to the needs of the department and the broader institution.
                
                In alignment with our commitment to pay transparency, the base salary range for this position is listed above (exclusive of benefits and retirement). 
                At UMass Chan Medical School, final base salary offers are determined based on a combination of factors, including your skills, education, and relevant experience. 
                We also consider internal equity to ensure fair and consistent compensation across our teams.
                
                Please note that the range provided reflects the full base salary range for this position. Offers are typically made within the midrange to allow for future growth and development within the role.
                
                In addition to base pay, UMass Chan offers a comprehensive Total Rewards package, which includes paid time off, medical, dental, and vision coverage, and participation in a 401(a)-retirement plan, with the option to contribute to a voluntary 403(b) plan.
                
                UMass Chan welcomes all qualified applicants and complies with all state and federal anti-discrimination laws.