SEARCH CAREER OPPORTUNITIES

POSITION SUMMARY: 

Under the general direction of the principal investigator and facility director, the Senior Research Scientist performs a variety of complex research experiments for research projects mainly using Cryo-electron microscopy and Cryo-electron tomography.  Supervises and provides services to cryo-EM academic users and industry customers.

ESSENTIAL FUNCTIONS:

Research:

• Design and implement research projects in the facility laboratory.
• Stay current with the literature and regularly leads discussions of new reports pertinent to ongoing and proposed projects.
• Design and implement experiments to further ongoing research projects, in consultation with the principal investigator.
• Responsible for data acquisition, data analysis, and presentation of research results.
• Organize and analyze data acquired in the course of research projects.
• Specific expertise in the cryoEM is required including preparing cryoEM grids in variers conditions using manual and automated cryo plunger freezers.

Mentorship:

• Train and supervise junior facility personnel and CryoEM users and customers, ensuring them are trained in current methodology and safety procedures in the laboratory.
• Participate regularly in laboratory meetings.
• Navigate and train the diverse personalities that make up our dynamic facility environment.
• Provide support for under-represented minorities scholars.
• Ensure researchers in the laboratory are aware of the experimental nuances and potential risks of their experiments – that they are using the optimal approach to obtain quality data.

Facility Operations:

• Lead and coordinate the general operation of the laboratory, in consultant with facility manager.
• Perform routine maintenance to cryo-electron microscopy instruments to ensure they are in excellent operating conditions.
• Interface with CryoEM academic users and industry customers, provide advice for experimental strategies of sample preparation and data acquisition.
• Acquire high-resolution data for customers when needed and monitor data collection quality and efficiency throughout the session.
• Analyze CryoEM structural data for customer when needed.
• Provide service report to external customers for the sample characterization services.
• Perform other duties as required.

REQUIRED QUALIFICATIONS:

• Bachelor’s degree in a Biological Science, or equivalent degree
• 7 years of research experience.
• PhD in a Biological Science preferred with 5 years of research experience.
• Familiarity with high-end cryo-electron microscopes and director electron detectors.
• Expertise in imaging processing for both single particle and cryo-ET applications.
• Familiarity with Linux operating system.
• Oral and written communication and presentation skills.
• Ability to work off-hours occasionally.

PREFERRED QUALIFICATIONS:

Experience with Cryo-FIB instrument and procedure of making cryo lamella.