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Research Scientist, Sr
Job Number: 2022-39333
Category: Research
Location: Worcester, MA
Shift: Day
Exempt/Non-Exempt: Exempt
Business Unit: UMass Chan Medical School
Department: School - Molecular Medicine - W400900
Job Type: Full-Time
Salary Grade: 46
Num. Openings: 1
Post Date: Sept. 26, 2022


The successful candidate will join a dynamic laboratory group that includes graduate students, postdoctoral fellows with PhD or MD degrees and staff scientists devoted to unraveling the molecular mechanisms associated with metabolic diseases such as obesity and diabetes. Exciting new results obtained by the laboratory have now enabled major long-term funding by the NIH and Department of Defense to advance the team’s work towards therapeutic strategies to prevent and cure type 2 diabetes and other related diseases. We seek new team members with enthusiasm for science and the transformative possibilities that come with new technologies such as RNAi and CRISPR as applied to conquer human disease. 

Under the general direction of the Principle Investigator, the Senior Research Scientist performs a variety of complex research experiments laboratory research on topics pertinent to the interests of the research programs of the laboratory. 



  • Design and implement experiments designed to further ongoing research projects, in consultation with the principal investigator.
  • Organize and analyze data acquired in the course of research projects.
  • Write manuscripts and grant applications
  • Design and implement research projects in the laboratory
  • Responsible for data acquisition, data analysis, and presentation of research results. 
  • Train and supervise junior lab personnel, ensuring staff is trained in current methodology and safety procedures in the laboratory.
  • Prepare and present data for publication in public forums.
  • Assist in the preparation of grant applications and other research proposals.
  • Provide assistance in the general operation of the laboratory.
  • Participate regularly in laboratory meetings.
  • Stay current with the literature and regularly leads discussions of new reports pertinent to ongoing and proposed projects
  • Perform other duties as required.



  • Bachelor’s degree in a Biological Science, or equivalent degree
  • 7 years of research experience.
  • Familiarity with general laboratory procedures.
  • Expertise in specific procedures and instrumentation necessary to complete specific research programs.
  • Current knowledge of pertinent literature.
  • Oral and written communication and presentation skills
  • Ability to travel to off-site locations


  • Experience (or willingness) in enthusiastically applying skills in molecular and cell biology to such methods as RT-PCR, Protein Chemistry, Light sheet and other types of microscopy and metabolic assays in both in vitro and in vivo model systems.
  • Experience (or willingness) in using a variety of mouse models that are available in our laboratory for testing and advancing therapeutic strategies for type 2 diabetes and other diseases. 


Under the general direction of the Principle Investigator


Supervises and trains new laboratory personnel and junior members of the laboratory


Wet chemistry laboratory, and may require appropriate contact with biohazards, radionuclides, toxins, animals, and human specimens. 

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