
GENERAL SUMMARY OF POSITION:
The Ramirez-Ortiz lab focuses understanding the role of mammalian Scavenger Receptors (SR), Toll-like Receptors (TLRs) and Triggering Receptor expressed on Myeloid Cells (TREM) in innate immune responses to a myriad of danger molecules derived from foreign and self-host sources. Specifically, we study the role and molecular mechanism of this receptors in clearance of apoptotic cells. Failure of this essential process leads to the accumulation of apoptotic cells. Therefore, impaired apoptotic cell uptake results in the loss of immune self-tolerance and development of Systemic Lupus Erythematous.
Lab website: https://www.umassmed.edu/ramirezortizlab/
Under the direction of the Principal Investigator or designee, the Research Associate I performs a variety of complex research experiments.
MAJOR RESPONSIBILITIES:
REQUIRED QUALIFICATIONS:
SUPERVISION RECEIVED:
Under the direction of the Principal Investigator, or designee
SUPERVISION EXERCISED:
May functionally supervise aides, technicians, and associates
ENVIRONMENTAL WORKING CONDITIONS:
Wet chemistry laboratory, and may require appropriate contact with biohazards, radionuclides, toxins, animals, and human specimens.
UMass Chan Medical School was among 23 companies that stood out as 2023 “DEI champions,” according to The Boston Globe.