SEARCH CAREER OPPORTUNITIES

POSITION SUMMARY: 

We currently have an opening for a Research Associate I to join the laboratory of Dr. Michelle Kelliher at the University of Massachusetts Chan Medical Center. The Kelliher lab studies how leukemia develops using genetically engineered mouse models and patient derived xenografts. We are focused on understanding the molecular and cellular basis of chemoresistance and relapse in an effort to develop novel therapeutic approaches. Our lab uses innovative mouse modeling approaches and single cell sequencing and chromatin accessibility methods to identify features of leukemic stem or initiating cells thought to mediate relapse. This position offers opportunities for career development, including possibly designing and executing independent experiments which could lead to publication.

ESSENTIAL FUNCTIONS:

• Perform laboratory experiments and may be responsible for a single research project
• Utilize all software relevant to experiment and equipment used
• Interpret data, form conclusions and decide on next steps under the direction of the PI or designee
• Maintain accurate records, may modify protocols with the approval of the PI or designee
• Review literature, publications and grants relevant to assigned projects
• Record results according to established lab, sponsor & university protocol
• Assist with performing data analysis and/or mathematical computations
• Maintain a detailed lab notebook according to lab practice
• Present findings at lab/group meetings
• Monitor laboratory supply levels and order as noted
• Prepare and label buffers, media, solutions, etc.
• Assist with and comply with all safety regulation and infection control standards
• Train on IACUC, IRB, EHS, Radiation safety protocols
• Comply with all applicable state, federal university, and sponsor policies and agreements
• Provide support with identifying problems and challenges, propose resolutions, implement appropriate solutions
• Provide support with drafting standard operation procedures in compliance to EHS regulation specific for the lab
• Perform other duties as required

REQUIRED QUALIFICATIONS:

• Bachelors degree in Biological or Natural Science, or equivalent experience
• Basic understanding of lab safety and protocols
• Knowledge of Microsoft Office products
• Ability to analyze data in a quantitative and objective manner.
• Ability to work in a team environment

SUPERVISION RECEIVED:

Under the direction of the Principal Investigator, or designee

SUPERVISION EXERCISED: 

May functionally supervise Lab Technicians and Aides

ENVIRONMENTAL WORKING CONDITIONS:

Wet chemistry laboratory, and may require appropriate contact with biohazards, radionuclides, toxins, animals, and human specimens. 

 Preferred Qualifications:

• Mouse experience is highly desired but not required
• Self-motivated, detail-oriented, and able to perform complex tasks effectively and independently with general instruction
• Ability to work in a team-focused environment
• Excellent communication and computer skills