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Bioinformatician II
Job Number: 2021-38451
Category: Information Technology
Location: Worcester, MA
Shift: Day
Exempt/Non-Exempt: Exempt
Business Unit: UMass Chan Medical School
Department: School - Molecular Cell & Cancer Biology - W495000
Job Type: Full-Time
Salary Grade: 73
Num. Openings: 1
Post Date: Sept. 21, 2021

GENERAL SUMMARY OF POSITION:

Under the direction of a member of the faculty, the Bioinformatician is responsible for the design, development, evaluation and iterative modification of a technical infrastructure to expedite the quantitative evaluation of data resulting from studies that are laboratory based.  The position will entail the establishment and maintenance of applicable in-house bioinformatics resources and interaction with individual lab members on customized research projects, as well independent projects that are solely computational. 

MAJOR RESPONSIBILITIES:

  • Establish general bioinformatics resources for day-to-day use by members of the laboratory.
  • In collaboration with a member of the faculty, generate customized programming solutions to improve user interaction with available bioinformatics resources
  • Implement and adapt programs for microarray analysis, high-throughput sequencing data analysis, cis regulatory motif identification, and multi-genome protein motif searches.
  • Independently develop, implement and maintain custom designed computational solutions relevant for ongoing lab-based projects.
  • Independently develop, implement and maintain computational methods for meta-analysis of data generated in the lab as well as publicly available data.
  • Independently execute a scientific computational project (e.g. a project that can result in a first author publication)
  • Local establishment and customization of model organism genomic databases and tools for batch sequence analysis utilizing these resources.
  • Interpret and present study results in support of laboratory members.
  • Provide tabular and written summaries of approaches and analyses in a form suitable for inclusion in manuscripts or grant applications, as well as media for presentation at scientific meetings
  • Develop and implement custom bioinformatics programming solutions in collaboration with lab as necessary
  • Coordinate and collaborate with other research computing expertise at the Medical School as necessary
  • Participate in conference calls and data management meetings as needed
  • Perform other duties as required

REQUIRED QUALIFICATIONS:

  • BS in computer science, or equivalent experience
  • 1-3 years of related experience
  • Co-authorships on peer-reviewed publications are strongly suggested but not required
  • Strong background in statistical methodology, software languages and computer systems (Perl, C++, R, MySQL, etc.)
  • Experience in writing basic search algorithms and the ability to generate new algorithms and programs for custom data manipulation and analysis
  • Excellent communication skills, both oral and written, and interpersonal skills necessary to interact with a wide range of individuals.

GENERAL SUMMARY OF POSITION:

Under the general direction of a member of the faculty or designee, the Bioinformatician III is responsible for developing novel algorithms and scientific software applications as well as providing bioinformatics data analysis support for research projects.

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MAJOR RESPONSIBILITIES:

  • Design and implement reusable bioinformatics analysis pipelines for processing next-generation sequencing, microarray, genomics, proteomics and drug screening data.
  • Integrate computational methods/pipelines with high performance computing clusters.
  • Collaborate closely with PIs and their lab members on research projects including defining the scope of the collaboration, researching on the scientific topics and implementing the appropriate bioinformatics solutions that meet timelines.
  • Participates in the oral presentation of all project findings and abstracts including participation in periodic project status meetings and presentation of final project deliverables.
  • Develop rapid prototypes and custom scripts for one-off type of analysis requests.
  • Develop novel algorithms and integrated data analysis and visualization applications when existing software packages are not available or adequate.
  • Properly document the procedures used in computational analysis and provide summary report of results suitable for inclusion in manuscript and grant applications.
  • Local establishment and customization of genomic, proteomics databases and provide batch analysis utilities that make use of these resources.
  • Independently develop, implement and maintain computational methods for meta-analysis of data generated in the lab as well as publicly available data.
  • Independently execute a scientific computational project (e.g. a project that can result in a first author publication)
  • Develop custom databases and web portals for managing raw and processed experimental data.
  • Provide bioinformatics training and workshops for analysis pipelines and in-house developed software applications.
  • Coordinate and collaborate with other bioinformaticians, biostatisticians, information technology professionals, and interdepartmental project teams.
  • Perform other duties as required.

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REQUIRED QUALIFICATIONS:

  • BS in Bioinformatics, computer science, or related computational discipline
  • 1-3 years of related experience
  • Co-authorships on peer-reviewed publications are strongly suggested but not required
  • Strong background in Bioinformatics, statistical methodology, software languages and computer systems (R, python, C/C++, MySQL, shell, etc.)
  • Excellent communication skills, both oral and written, and interpersonal skills necessary to interact with a wide range of individuals.
  • Strong project management skills.
  • Experience with next generation sequencing data analysis in high performance computing environment

 PREFERRED QUALIFICATIONS:

  • Experience with machine learning methodologies and natural language processing.
  • Experience in developing R packages and database web applications.
  • MS in Bioinformatics, Computer Science, or related computational discipline
  • Co-authorships on peer-reviewed publications

SUPERVISION RECEIVED:

Under the direction of a member of the faculty or designee

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SUPERVISION EXERCISED:

None

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ENVIRONMENTAL WORKING CONDITIONS:

Usual office environment

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As an equal opportunity and affirmative action employer, UMMS recognizes the power of a diverse community and encourages applications from individuals with varied experiences, perspectives and backgrounds.

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