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Research Associate I
Job Number: 2018-31896
Category: Research
Location: Worcester, MA
Shift: Day
Exempt/Non-Exempt: Exempt
Business Unit: UMass Chan Medical School
Department: School - Neurology - W832500
Job Type: Full-Time
Salary Grade: 42
Num. Openings: 1
Post Date: Jan. 17, 2019

GENERAL SUMMARY OF POSITION:  

Under the direction of the Principal Investigator or designee, the Research Associate I performs a variety of complex research experiments.

We are seeking an exceptional, highly-motivated and proactive individual to join our group as a mammalian cell culture specialist with the ability to perform molecular biology and biochemistry experiments. The position’s responsibilities will include designing and performing experiments, processing, interpreting and reporting data. 

MAJOR RESPONSIBILITIES:

  • Perform complex laboratory experiments
  • Conduct in-depth analysis of research experiments
  • Interpret data, form conclusions, and decide on and plan the next experiments to be done with a high degree of independence
  • Write standard operating procedures, schedule work, analyze data, maintain accurate records, and write reports
  • Compile and analyze data. Perform computations using image analysis software, spreadsheets, graphing, and curve fitting software
  • May modify protocols and be responsible for a single, independent research project
  • May assist with budget and/or operational aspects of grant and contract proposals
  • Assist in writing the text of scientific publications and grants.  Review literature
  • Train new laboratory personnel, students, and collaborators
  • Comply with all safety and infection control standards
  • Perform other duties as required.

                               

 

REQUIRED QUALIFICATIONS:  

  • Bachelor’s degree in the Biological Sciences, or equivalent experience
  • 3 years of relevant research experience
  • Knowledge of Microsoft Office products
  • Strong ability to analyze complex visual data in a quantitative and objective manner
  • Judgment and action skills required to solve commonly encountered problems

ADDITIONAL SKILLS:

Cellular Biology

  • Growing and maintaining cell lines and primary cells
  • Transfecting/ transducing cell lines and downstream characterization experiments
  • Lysing cells for protein analysis techniques

 Molecular Biology

  • General DNA and RNA manipulation technologies
  • PCR, qPCR, restriction digests, site-directed mutagenesis, RNA and DNA isolation, vector construction knowledge/ expertise
  • Gel electrophoresis, sequence analysis, nanodrop quantitation of nucleic acids
  • Transient transfection and lentiviral transduction, siRNA and shRNA techniques
  • General protein manipulation technologies
  • Western blotting, Immunoprecipitation and ELISA
  • immunofluorescence

Other

  • Expertise in data analysis and presentation software: MS Powerpoint, MS Excel, MS Word, GraphPad Prism.
  • Be able to perform data analysis, data quality control and data interpretation

SUPERVISION RECEIVED:

Under the direction of the Principal Investigator, or designee

 

SUPERVISION EXERCISED: 

May functionally supervise aides, technicians, and associates

ENVIRONMENTAL WORKING CONDITIONS:

Wet chemistry laboratory, and may require appropriate contact with biohazards, radionuclides, toxins, animals, and human specimens.

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